Nicotinamide (Vitamin B3): Nicotinamide has been shown in multiple studies to improve acne, reduce redness, and strengthen the skin barrier. In one study, it outperformed topical antibiotics in reducing inflammation and improving skin texture.
Summary: This study found that oral nicotinamide reduced sebum production and inflammatory lesions in acne patients. It showed comparable results to antibiotics without the side effects, making it a well-tolerated option for inside-out skin support.
Other reviews and trials highlight nicotinamide’s ability to restore the skin barrier, reduce redness, and regulate oil from within.
Link to Study: Oral nicotinamide reduces sebum production and inflammation in acne patients
(This study showed that oral nicotinamide reduced sebum production and inflammation - two key acne triggers.)
Other Studies:
1. The Nicomide Improvement in Clinical Outcomes Study (NICOS)
(Oral nicotinamide combined with zinc, copper, and folic acid significantly improved acne and rosacea symptoms, matching the effectiveness of antibiotics without their side effects.)
2. The Role of Nicotinamide in Acne Treatment
(Both oral and topical nicotinamide showed significant acne reduction with no major side effects, highlighting its anti-inflammatory benefits.)
3. Dietary Supplements for Acne: A Systematic Review